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dc.contributor.authorRibeiro, LFC
dc.contributor.authorChelius, C
dc.contributor.authorBoppidi, KR
dc.contributor.authorNaik, NS
dc.contributor.authorHossain, S
dc.contributor.authorRamsey, JJJ
dc.contributor.authorKumar, J
dc.contributor.authorRibeiro, LF
dc.contributor.authorOstermeier, M
dc.contributor.authorTran, B
dc.contributor.authorAh Goo, Y
dc.contributor.authorde Assis, LJ
dc.contributor.authorUlas, M
dc.contributor.authorBayram, O
dc.contributor.authorGoldman, GH
dc.contributor.authorLincoln, S
dc.contributor.authorSrivastava, R
dc.contributor.authorHarris, SD
dc.contributor.authorMarten, MR
dc.contributor.editorLin X
dc.date.accessioned2024-02-27T13:48:28Z
dc.date.available2024-02-27T13:48:28Z
dc.date.issued2019-04-30
dc.identifier.issn2161-2129
dc.identifier.issn2150-7511
dc.identifier.otherARTN e02825-18
dc.identifier.urihttps://pearl.plymouth.ac.uk/handle/10026.1/22097
dc.description.abstract

<jats:p>The cyclic AMP (cAMP)-dependent protein kinase A (PKA) signaling pathway is well conserved across eukaryotes, and previous work has shown that it plays an important role in regulating development, growth, and virulence in a number of fungi. PKA is activated in response to extracellular nutrients and acts to regulate metabolism and growth. While a number of components in the PKA pathway have been defined in filamentous fungi, current understanding does not provide a global perspective on PKA function. Thus, this work is significant in that it comprehensively identifies proteins and functional pathways regulated by PKA in a model filamentous fungus. This information enhances our understanding of PKA action and may provide information on how to manipulate it for specific purposes.</jats:p>

dc.format.extente02825-e02818
dc.format.mediumElectronic
dc.languageen
dc.publisherAmerican Society for Microbiology
dc.subjectCreA
dc.subjectphosphoproteomic
dc.subjectphosphosite
dc.subjectsignal transduction
dc.subjecttranscriptomic
dc.titleComprehensive Analysis of Aspergillus nidulans PKA Phosphorylome Identifies a Novel Mode of CreA Regulation
dc.typejournal-article
dc.typeArticle
plymouth.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/31040248
plymouth.issue2
plymouth.volume10
plymouth.publisher-urlhttp://dx.doi.org/10.1128/mbio.02825-18
plymouth.publication-statusPublished
plymouth.journalmBio
dc.identifier.doi10.1128/mbio.02825-18
plymouth.organisational-group|Plymouth
plymouth.organisational-group|Plymouth|Faculty of Health
plymouth.organisational-group|Plymouth|REF 2021 Researchers by UoA
plymouth.organisational-group|Plymouth|Users by role
plymouth.organisational-group|Plymouth|Users by role|Academics
plymouth.organisational-group|Plymouth|REF 2021 Researchers by UoA|UoA01 Clinical Medicine
plymouth.organisational-group|Plymouth|Faculty of Health|Peninsula Medical School
plymouth.organisational-group|Plymouth|REF 2028 Researchers by UoA
plymouth.organisational-group|Plymouth|REF 2028 Researchers by UoA|UoA01 Clinical Medicine
dc.publisher.placeUnited States
dc.date.updated2024-02-27T13:48:26Z
dc.identifier.eissn2150-7511
dc.rights.embargoperiodforever
rioxxterms.versionofrecord10.1128/mbio.02825-18


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