Reproductive and whole-body toxicity of Ag-doped and -undoped ZIF-8 nanoparticles and the building blocks: An Artemia-based comparative bioassay
dc.contributor.author | Salari Joo, H | |
dc.contributor.author | Johari, SA | |
dc.contributor.author | Behzadi Tayemeh, M | |
dc.contributor.author | Handy, RD | |
dc.contributor.author | Abaei, H | |
dc.contributor.author | Clark, N | |
dc.contributor.author | Seyedi, J | |
dc.contributor.author | Jones, MA | |
dc.date.accessioned | 2024-02-05T11:06:42Z | |
dc.date.available | 2024-02-05T11:06:42Z | |
dc.date.issued | 2024-02-01 | |
dc.identifier.issn | 0269-7491 | |
dc.identifier.issn | 1873-6424 | |
dc.identifier.other | 123141 | |
dc.identifier.uri | https://pearl.plymouth.ac.uk/handle/10026.1/22017 | |
dc.description.abstract |
The present research assessed, for the first time, toxicity of ZIF-8 (1 mg/L) and the building blocks (0.1 mg/L Zn2+ and 0.4 mg/L 2-methylimidazole (2-MIm)), besides that of AgNPs@ZIF-8 (0.25, 0.5, and 1 mg/L) and AgNO3 (0.1 mg/L) to aquatic organisms. Two consecutive generations (F0 & F1) of Artemia salina were exposed to these chemicals. All of the chemical treatments considerably caused mortality in F0, especially AgNPs@ZIF-8 and AgNO3, whereas F1 displayed notable tolerance and survived comparable to the control group, except in the case of AgNO3 treatment. Similarly, growth indices (weight, mainly in ZIF-8, Zn2+, and 2-MIm; length, in Ag-doped ZIF-8 and AgNO3) were significantly retarded in F0 and especially F1 of all treatments, and 2-MIm caused the greatest length retardation in F0. AgNPs@ZIF-8 (0.5 and 1 mg/L), 2-MIm, and AgNO3 postponed the ovary emergence in about 40%–60% of the exposed F0, and ZIF-8 delayed this phenomenon in some individuals of F0 and F1 up to 6 days. This temporal disturbance was also observed in time to first brood of almost all experimental F0 and F1 groups, with being over 80% of F1 exposed to ZIF-8, 2-MIm, and Zn2+, as well as about 50% of F0 treated with 2-MIm, and Zn2+. The highest neonate number was recorded for F0 and F1 exposed to AgNO3 and Zn2+, while ZIF-8 and, importantly, 2-MIm decreased the reproductivity to the lowest levels in both generations. Generally, the reproductive frequency was significantly decreased in all F0 and F1 treatments, especially 2-MIm, ZIF-8, AgNPs@ZIF-8 (0.25 & 1 mg/L). This study highlighted the neglected importance of 2-MIm in assessing overall toxicity of ZIF-8, and even other organic ligands of MOFs, and also filled a gap in the literature by investigating the potential effect of additives such as AgNPs on the toxicity of ZIF-8 and other MOFs. | |
dc.format.extent | 123141-123141 | |
dc.format.medium | Print-Electronic | |
dc.language | en | |
dc.publisher | Elsevier BV | |
dc.subject | 2-Methylimidazole | |
dc.subject | Growth performance | |
dc.subject | Nanoparticles | |
dc.subject | Neonate number | |
dc.subject | Organic ligand | |
dc.subject | Reproduction | |
dc.title | Reproductive and whole-body toxicity of Ag-doped and -undoped ZIF-8 nanoparticles and the building blocks: An Artemia-based comparative bioassay | |
dc.type | journal-article | |
dc.type | Article | |
plymouth.author-url | https://www.ncbi.nlm.nih.gov/pubmed/38097159 | |
plymouth.volume | 342 | |
plymouth.publisher-url | http://dx.doi.org/10.1016/j.envpol.2023.123141 | |
plymouth.publication-status | Published | |
plymouth.journal | Environmental Pollution | |
dc.identifier.doi | 10.1016/j.envpol.2023.123141 | |
plymouth.organisational-group | |Plymouth | |
plymouth.organisational-group | |Plymouth|Research Groups | |
plymouth.organisational-group | |Plymouth|Faculty of Health | |
plymouth.organisational-group | |Plymouth|Faculty of Health|School of Health Professions | |
plymouth.organisational-group | |Plymouth|Faculty of Science and Engineering | |
plymouth.organisational-group | |Plymouth|Faculty of Science and Engineering|School of Biological and Marine Sciences | |
plymouth.organisational-group | |Plymouth|Research Groups|Marine Institute | |
plymouth.organisational-group | |Plymouth|REF 2021 Researchers by UoA | |
plymouth.organisational-group | |Plymouth|Users by role | |
plymouth.organisational-group | |Plymouth|Users by role|Academics | |
plymouth.organisational-group | |Plymouth|REF 2021 Researchers by UoA|UoA06 Agriculture, Veterinary and Food Science | |
plymouth.organisational-group | |Plymouth|REF 2028 Researchers by UoA | |
plymouth.organisational-group | |Plymouth|REF 2028 Researchers by UoA|UoA02 Public Health, Health Services and Primary Care | |
plymouth.organisational-group | |Plymouth|REF 2028 Researchers by UoA|UoA06 Agriculture, Veterinary and Food Science | |
dc.publisher.place | England | |
dcterms.dateAccepted | 2023-12-09 | |
dc.date.updated | 2024-02-05T11:06:41Z | |
dc.rights.embargodate | 2025-12-11 | |
dc.identifier.eissn | 1873-6424 | |
rioxxterms.versionofrecord | 10.1016/j.envpol.2023.123141 |